Found 3 Enz. Inhib. hit(s) with Target = 'Methylosome protein 50/Protein arginine N-methyltransferase 5' and Ligand = 'BDBM50607732' TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKi: 862nMAssay Description:Binding affinity to PRMT5/MEP50 (unknown origin) assessed as inhibition constant by FITC- Competitive binding assayMore data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of PRMT5/MEP50 (unknown origin) incubated for 1 to 2 hrs in presence of tracer 21 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of PRMT5/MEP50 (unknown origin) incubated for 1 to 2 hrs in presence of tracer 50 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
