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Found 2 Enz. Inhib. hit(s) with Target = 'Methylosome protein 50/Protein arginine N-methyltransferase 5' and Ligand = 'BDBM515307'
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM515307(6'-(1-cyclopropyl-1H-1,2,4- triazol-5-yl)-2'-{(2R)...)
Affinity DataIC50:  0.290nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a twenty-point (1:2 serial dilution; top compound concentration of 100000 nM) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM515307(6'-(1-cyclopropyl-1H-1,2,4- triazol-5-yl)-2'-{(2R)...)
Affinity DataIC50:  127nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a twenty-point (1:2 serial dilution; top compound concentration of 100000 nM) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent