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Found 2 Enz. Inhib. hit(s) with Target = 'Microsomal triglyceride transfer protein large subunit' and Ligand = 'BDBM50391864'
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50391864(CHEMBL2147287)
Affinity DataIC50:  0nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50391864(CHEMBL2147287)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed