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Found 1 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM15616'
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM15616(4-(3-chlorophenyl)-3-[5-(pyrrolidin-1-ylcarbonyl)-...)
Affinity DataKi:  200nM ΔG°:  -38.9kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by ERK2 was converted to ATP by pyruvate kinase with the production of pyruvate fr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed