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Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 11' and Ligand = 'BDBM50492386'
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50492386(CHEMBL2401979)
Affinity DataIC50:  4nMAssay Description:Inhibition of p38beta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50492386(CHEMBL2401979)
Affinity DataIC50:  4nMAssay Description:Inhibition of human p38beta expressed in Escherichia coli using MBP as substrate preincubated for 10 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50492386(CHEMBL2401979)
Affinity DataKd:  6.20nMAssay Description:Binding affinity to human p38beta expressed in Escherichia coli by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed