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Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM236619'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236619(US9388136, Table 1, Compound 11:Cyclopentyl (2S)-4...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236619(US9388136, Table 1, Compound 11:Cyclopentyl (2S)-4...)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent