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Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50382374'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382374(CHEMBL2024530)
Affinity DataIC50:  750nMAssay Description:Inhibition of p38alpha kinase using KRELVEPLTPSGEAPNQALLR as substrate for 20 mins by lactate dehydrogenase-coupled spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382374(CHEMBL2024530)
Affinity DataIC50:  980nMAssay Description:Inhibition of p38alpha in human PBMC assessed as inhibition of LPS-induced IL1beta production after 16 to 18 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382374(CHEMBL2024530)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of p38alpha in human PBMC assessed as inhibition of LPS-induced TNFalpha production after 16 to 18 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed