Found 9 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50425360' TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of T£Bingen
Curated by ChEMBL
University Of T£Bingen
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of p38alpha MAP kinase (unknown origin) by ELISAMore data for this Ligand-Target Pair
3D Structure (crystal)TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of T£Bingen
Curated by ChEMBL
University Of T£Bingen
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of P38 alpha MAPK (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of T£Bingen
Curated by ChEMBL
University Of T£Bingen
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p38alpha MAPK expressed in baculovirus infected Sf9 insect cells using p38 peptide ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of T£Bingen
Curated by ChEMBL
University Of T£Bingen
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of NanoBRET kinase tracer K4 binding to full-length human C-terminal NanoLuc-tagged p38alpha MAPK expressed in HEK293T cells incubated for...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of T£Bingen
Curated by ChEMBL
University Of T£Bingen
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of p38alpha MAP kinase in whole blood (unknown origin) assessed as lipopolysaccharide-stimulated TNF-alpha release by ELISAMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of T£Bingen
Curated by ChEMBL
University Of T£Bingen
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of p38alpha MAPK in human whole blood assessed as reduction in LPS-induced TNFalpha production preincubated for 2.5 hrs followed by LPS st...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of T£Bingen
Curated by ChEMBL
University Of T£Bingen
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of P38 alpha MAPK in human whole blood assessed as reduction in TNF-alpha release after 10 mins by ELISAMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of T£Bingen
Curated by ChEMBL
University Of T£Bingen
Curated by ChEMBL
Affinity DataKd: 3.10nMAssay Description:Binding affinity to wild type human biotin labelled p38 alpha (9 to 352 residues) expressed in sf21 insect cells SPR analysisMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of T£Bingen
Curated by ChEMBL
University Of T£Bingen
Curated by ChEMBL
Affinity DataKd: 3.90nMAssay Description:Binding affinity to wild type human biotin labelled p38 alpha (9 to 352 residues) expressed in sf21 insect cells assessed as dissociation rate consta...More data for this Ligand-Target Pair
