Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 6' and Ligand = 'BDBM50553821'
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553821(CHEMBL4741134)
Affinity DataIC50:  13nMAssay Description:Inhibition of ERK3 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553821(CHEMBL4741134)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 471 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553821(CHEMBL4741134)
Affinity DataIC50:  33nMAssay Description:Inhibition of recombinant full length His6-GST fusion tagged ERK3 (1 to 721 residues) (unknown origin) using MK5 K51A mutant as substrate by ADP-Glo ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553821(CHEMBL4741134)
Affinity DataIC50:  55nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 365 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553821(CHEMBL4741134)
Affinity DataKd:  23nMAssay Description:Binding affinity to wild-type human partial length ERK3 (M1 to P413 residues) expressed in bacterial expression system by kinomescan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed