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Found 5 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 6' and Ligand = 'BDBM50553822'
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553822(CHEMBL4757911)
Affinity DataIC50:  55nMAssay Description:Inhibition of ERK3 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553822(CHEMBL4757911)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 471 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553822(CHEMBL4757911)
Affinity DataIC50:  177nMAssay Description:Inhibition of recombinant full length His6-GST fusion tagged ERK3 (1 to 721 residues) (unknown origin) using MK5 K51A mutant as substrate by ADP-Glo ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553822(CHEMBL4757911)
Affinity DataIC50:  244nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 365 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553822(CHEMBL4757911)
Affinity DataKd:  200nMAssay Description:Binding affinity to wild-type human partial length ERK3 (M1 to P413 residues) expressed in bacterial expression system by kinomescan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB