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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 12' and Ligand = 'BDBM50271240'
LigandPNGBDBM50271240(CHEMBL3718522)
Affinity DataKi:  16nMAssay Description:Binding affinity to N-terminally GST-tagged wild type human DLK (1 to 520 residues) expressed in sf21 insect cells using N-terminally His-tagged MKK4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50271240(CHEMBL3718522)
Affinity DataIC50:  180nMAssay Description:Inhibition of doxycycline inducible human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed