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Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 1' and Ligand = 'BDBM50563731'
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM50563731(CHEMBL4799073 | US11453681, Compound C44)
Affinity DataIC50:  0.0500nMAssay Description:The enzymatic activity of human HPK1 (MAP4K1) was monitored in a biochemical assay in the presence or absence of compounds and using a synthetic pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM50563731(CHEMBL4799073 | US11453681, Compound C44)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of recombinant human HPK1 expressed in baculovirus infected insect cells using SRKS1 peptide as substrate incubated for 15 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed