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Found 2 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M4' and Ligand = 'BDBM372325'
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM372325(N-cyclopropyl-7,9-dimethyl- pyrido[3',2':4,5]furo[...)
Affinity DataEC50:  2.60E+3nMAssay Description:Positive allosteric modulation of human muscarinic acetylcholine M4/Gqi5 receptor expressed in CHO cells in presence of acetylcholine at EC20 concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM372325(N-cyclopropyl-7,9-dimethyl- pyrido[3',2':4,5]furo[...)
Affinity DataEC50:  2.60E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent