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Found 2 Enz. Inhib. hit(s) with Target = 'Myeloperoxidase' and Ligand = 'BDBM492848'
TargetMyeloperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM492848(7-(((1-phenyl-3- (trifluoromethyl)-1H- pyrazol-4-y...)
Affinity DataIC50:  10nMAssay Description:MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyeloperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM492848(7-(((1-phenyl-3- (trifluoromethyl)-1H- pyrazol-4-y...)
Affinity DataIC50:  20nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog #A12222) which ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent