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Found 2 Enz. Inhib. hit(s) with Target = 'Myeloperoxidase' and Ligand = 'BDBM50507391'
TargetMyeloperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50507391(CHEMBL4594116 | US10981879, Example 153)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human PMN leukocytes MPO peroxidation activity using H2O2 as substrate preincubated for 10 mins followed by H2O2 addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50507391(CHEMBL4594116 | US10981879, Example 153)
Affinity DataIC50:  130nMAssay Description:MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent