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Found 7 Enz. Inhib. hit(s) with Target = 'N-formyl peptide receptor 2' and Ligand = 'BDBM50559829'
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50559829(CHEMBL4784510)
Affinity DataIC50:  7.5nMAssay Description:Agonist activity at human FPR2 in human HL-60 cells assessed as inhibition of chemotaxis by measuring reduction in cell migrationMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50559829(CHEMBL4784510)
Affinity DataIC50:  57nMAssay Description:Agonist activity at FPR2 in human HL-60 cells assessed as reduction in chemoattractant induced chemotaxis by luminescence cell viability assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50559829(CHEMBL4784510)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human FPR2 expressed in CHO-K1 cells assessed as stimulation of beta-arrestin recruitmentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50559829(CHEMBL4784510)
Affinity DataEC50:  1.25E+3nMAssay Description:Agonist activity at human FPR2 expressed in CHO-A12 cells assessed as cAMP level incubated for 1.5 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50559829(CHEMBL4784510)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human FPR2 overexpressing CHO cells assessed as reduction in intracellular cAMP level incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50559829(CHEMBL4784510)
Affinity DataEC50:  0.410nMAssay Description:Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50559829(CHEMBL4784510)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human FPR2 expressed in CHO cells assessed as reduction cAMP accumulation incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed