Found 2 Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacylase sirtuin-5, mitochondrial' and Ligand = 'BDBM50255692'
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Antagonist activity at human TLR4 expressed in mouse RAW blue cells assessed as inhibition of LPS-induced NF-kappaB activation-mediated SEAP producti...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair