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Found 3 Enz. Inhib. hit(s) with Target = 'Neuromedin-K receptor' and Ligand = 'BDBM50341074'
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen

Curated by ChEMBL
LigandPNGBDBM50341074((4-(2-methoxyphenyl)piperazin-1-yl)(3-phenyl-1H-py...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement [3H]SB-222200 from of human recombinant NK3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Rattus norvegicus)
Euroscreen

Curated by ChEMBL
LigandPNGBDBM50341074((4-(2-methoxyphenyl)piperazin-1-yl)(3-phenyl-1H-py...)
Affinity DataKi:  1.20E+4nMAssay Description:Binding affinity to rat NK3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen

Curated by ChEMBL
LigandPNGBDBM50341074((4-(2-methoxyphenyl)piperazin-1-yl)(3-phenyl-1H-py...)
Affinity DataIC50:  480nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed