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Found 7 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50061564'
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50061564((3E)-3-[(2,4-DIMETHOXYPHENYL)METHYLIDENE]-3,4,5,6-...)
Affinity DataKi:  220nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50061564((3E)-3-[(2,4-DIMETHOXYPHENYL)METHYLIDENE]-3,4,5,6-...)
Affinity DataKi:  886nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in rat brain membrane after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50061564((3E)-3-[(2,4-DIMETHOXYPHENYL)METHYLIDENE]-3,4,5,6-...)
Affinity DataKi:  886nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in rat brain membrane after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50061564((3E)-3-[(2,4-DIMETHOXYPHENYL)METHYLIDENE]-3,4,5,6-...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50061564((3E)-3-[(2,4-DIMETHOXYPHENYL)METHYLIDENE]-3,4,5,6-...)
Affinity DataEC50:  6.00E+3nMAssay Description:Partial agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes incubated for 90 secs followed by washout period for 5 mins by ele...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50061564((3E)-3-[(2,4-DIMETHOXYPHENYL)METHYLIDENE]-3,4,5,6-...)
Affinity DataKd:  158nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50061564((3E)-3-[(2,4-DIMETHOXYPHENYL)METHYLIDENE]-3,4,5,6-...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human recombinant alpha7 nAChR expressed in rat GH3 cells by calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed