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Found 6 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50161764'
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universite Orleans

Curated by ChEMBL
LigandPNGBDBM50161764((R)-4-chloro-N-(quinuclidin-3-yl)benzamide | (R)-4...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAchR in rat frontal corticesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universite Orleans

Curated by ChEMBL
LigandPNGBDBM50161764((R)-4-chloro-N-(quinuclidin-3-yl)benzamide | (R)-4...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]MLA from alpha7 nAChR in Sprague-Dawley rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universite Orleans

Curated by ChEMBL
LigandPNGBDBM50161764((R)-4-chloro-N-(quinuclidin-3-yl)benzamide | (R)-4...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]MLA from alpha-7 nACh receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50161764((R)-4-chloro-N-(quinuclidin-3-yl)benzamide | (R)-4...)
Affinity DataKi:  24.6nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50161764((R)-4-chloro-N-(quinuclidin-3-yl)benzamide | (R)-4...)
Affinity DataKi:  26nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50161764((R)-4-chloro-N-(quinuclidin-3-yl)benzamide | (R)-4...)
Affinity DataEC50:  40nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ul of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails