Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'Neuropeptide FF receptor 2' and Ligand = 'BDBM50336912'
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50336912(Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50336912(Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]FFRF-NH2 from human flag-tagged NPFF2 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50336912(Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...)
Affinity DataKi:  75nMAssay Description:Displacement of [125I]Tyr-NPFF from human NPFFR2 expressed in green monkey Cos-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50336912(Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...)
Affinity DataIC50:  410nMAssay Description:Antagonist activity at NPFF2 receptor (unknown origin) expressed in HEK293A cells assessed as reversal of NPPF induced inhibition of forskolin-stimul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50336912(Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...)
Affinity DataEC50:  379nMAssay Description:Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed