Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with Target = 'Neuropeptide S receptor' and Ligand = 'BDBM50443391'
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataKi:  48nMAssay Description:Binding affinity to human NPSR by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataIC50:  5.30nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as cAMP level after 30 mins by phosphate-buffered sal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataIC50:  25nMAssay Description:Displacement of [125I]Tyr10-NPS from human neuropeptide S receptor expressed in CHO cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataIC50:  48nMAssay Description:Displacement of [125I]Tyr10-NPS from neuropeptide S receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataIC50:  420nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataIC50:  420nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed