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Found 10 Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, inducible' and Ligand = 'BDBM50098937'
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)
Affinity DataIC50:  830nMAssay Description:Inhibition of human recombinant iNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)
Affinity DataIC50:  2.60E+3nMAssay Description:Compound was tested for for its inhibitory activity against macrophage NO2- synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory concentration against human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)
Affinity DataIC50:  8.00E+3nMAssay Description:In vitro inhibition of inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse BV2 cells measured after 24 hrs of post-stimulation by Griess reaction me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory activity of compound against human inducible nitiric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)
Affinity DataIC50:  1.40E+4nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)
Affinity DataIC50:  2.58E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)
Affinity DataIC50:  2.58E+4nMAssay Description:Inhibition of iNOS in mouse BV2 microglial cells assessed as NO productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)
Affinity DataIC50:  3.00E+8nMAssay Description:Inhibitory concentration against nitric oxide synthesis in intact DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed