Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Nociceptin receptor' and Ligand = 'BDBM50147749'
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50147749(1-(1-Cyclooctylmethyl-piperidin-4-yl)-1,3-dihydro-...)
Affinity DataKi:  6nMAssay Description:Binding affinity against human Nociceptin receptor on CHO cell membranes by [3H]N/OFQ displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50147749(1-(1-Cyclooctylmethyl-piperidin-4-yl)-1,3-dihydro-...)
Affinity DataKi:  6nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50147749(1-(1-Cyclooctylmethyl-piperidin-4-yl)-1,3-dihydro-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required for stimulation of [35S]-GTP-gammaS, binding NOP receptor in cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed