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Found 2 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM50445888'
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50445888(CHEMBL3105682)
Affinity DataIC50:  10nMAssay Description:Inhibition of APC-labeled RORgammat receptor ligand binding domain (unknown origin) after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Mus musculus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50445888(CHEMBL3105682)
Affinity DataIC50:  251nMAssay Description:Inhibition of RORgammat receptor ligand binding domain in mouse spleen CD4+ T cells assessed as inhibition of IL-17 production after 3 days by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed