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Found 2 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM50441375'
TargetOrexin receptor type 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50441375(CHEMBL2435402)
Affinity DataKi:  14nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK cells assessed as inhibition of orexin A-induced Ca2+ accumulation after 1 hr by Fluo-4-AM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Mus musculus)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50441375(CHEMBL2435402)
Affinity DataKi:  59nMAssay Description:Antagonist activity at mouse OX2 receptor expressed in HEK cells assessed as inhibition of orexin A-induced Ca2+ accumulation after 1 hr by Fluo-4-AM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed