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Found 3 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM514632'
TargetOrexin receptor type 2(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM514632(US11098029, Example 67)
Affinity DataIC50:  0.230nMAssay Description:Agonist activity at human recombinant OX2R expressed in CHOK1 cells assessed as increase in intracellular Ca2+ mobilization by measuring IP3 producti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM514632(US11098029, Example 67)
Affinity DataIC50:  0.460nMAssay Description:Agonist activity at human recombinant OX2R expressed in CHOK1 cells assessed as increase in intracellular Ca2+ mobilization by measuring IP3 producti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM514632(US11098029, Example 67)
Affinity DataIC50:  0.460nMAssay Description:In a typical experiment, the OX1 and OX2 receptor agonist activity is determined in accordance with the following general experimental method. Chines...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent