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Found 4 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM246968'
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM246968((S)-3-(2-chloro-3-(trifluoromethyl)phenyl)-5-methy...)
Affinity DataKi:  10.5nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM246968((S)-3-(2-chloro-3-(trifluoromethyl)phenyl)-5-methy...)
Affinity DataKi:  10.5nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM246968((S)-3-(2-chloro-3-(trifluoromethyl)phenyl)-5-methy...)
Affinity DataIC50:  1.60nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM246968((S)-3-(2-chloro-3-(trifluoromethyl)phenyl)-5-methy...)
Affinity DataIC50:  7.20nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent