Compile Data Set for Download or QSAR
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Found 5 Enz. Inhib. hit(s) with Target = 'Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1' and Ligand = 'BDBM34012'
LigandPNGBDBM34012(3-fluorophenylalanine derivative, 21b)
Affinity DataKi:  6nM ΔG°:  -45.4kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM34012(3-fluorophenylalanine derivative, 21b)
Affinity DataKi:  6nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM34012(3-fluorophenylalanine derivative, 21b)
Affinity DataIC50:  6nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM34012(3-fluorophenylalanine derivative, 21b)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human N-terminal His-tagged Pin1 expressed in Escherichia coli BL21 using Suc-Ala-Glu-Pro-Phe-4-nitroanilide as substrate i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM34012(3-fluorophenylalanine derivative, 21b)
Affinity DataIC50:  50nMAssay Description:Inhibition of human N-terminal His6-tagged Pin1 PPIase activity expressed in Escherichia coli BL21 using Suc-Ala-Glu-cis-Pro-Phe-4-nitroanilide as su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed