Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Phenylalanine--tRNA ligase alpha subunit' and Ligand = 'BDBM50140716'
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140716(5'-(3-chloro-4-methylphenyl)-3'-phenyl-(3'R,3a'S,6...)
Affinity DataIC50:  730nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140716(5'-(3-chloro-4-methylphenyl)-3'-phenyl-(3'R,3a'S,6...)
Affinity DataIC50:  990nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140716(5'-(3-chloro-4-methylphenyl)-3'-phenyl-(3'R,3a'S,6...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140716(5'-(3-chloro-4-methylphenyl)-3'-phenyl-(3'R,3a'S,6...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed