Found 1 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50427319' TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of PI3Kalpha-mediated AKT phosphorylation at threonine 308 in human BT474 cellsMore data for this Ligand-Target Pair
