Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform' and Ligand = 'BDBM50489452'
LigandPNGBDBM50489452(CHEMBL2322344)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50489452(CHEMBL2322344)
Affinity DataEC50:  2.51E+4nMAssay Description:Inhibition of PI3Kbeta human in PTEN-null MDA-MB-468 cells assessed as cell growth inhibitionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50489452(CHEMBL2322344)
Affinity DataEC50:  158nMAssay Description:Inhibition of PI3Kbeta human in PTEN-null MDA-MB-468 cells assessed as reduction of AKT phosphorylation at Ser 473 in absence of serumMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50489452(CHEMBL2322344)
Affinity DataEC50: <3.16E+4nMAssay Description:Inhibition of PI3Kbeta human in PTEN wild type HCC1954 cells assessed as reduction of AKT phosphorylation at Ser 473More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50489452(CHEMBL2322344)
Affinity DataEC50:  1.26E+4nMAssay Description:Inhibition of PI3Kbeta human in PTEN-null MDA-MB-468 cells assessed as reduction of AKT phosphorylation at Ser 473 in presence of serumMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50489452(CHEMBL2322344)
Affinity DataEC50: <3.16E+4nMAssay Description:Inhibition of PI3Kbeta human in PTEN wild type HCC1954 cells assessed as cell growth inhibitionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed