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Found 3 Enz. Inhib. hit(s) with Target = 'Platelet-activating factor acetylhydrolase' and Ligand = 'BDBM50429094'
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50429094(CHEMBL2335783)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli using 2- thio-PAF as substrate incubated for 20...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50429094(CHEMBL2335783)
Affinity DataIC50:  10nMAssay Description:Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50429094(CHEMBL2335783)
Affinity DataIC50:  59nMAssay Description:Inhibition of TAMRA-tagged AX4870 labeling of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli incubated for 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed