Found 4 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM50387918' 
Affinity DataKi: 3nMpH: 8.0Assay Description:PARP1 assay was conducted in PARP assay buffer containing 50 mM Tris pH 8.0, 1 mM DTT, 4 mM MgCl2. PARP reactions contained 1.5 uM [3H]-NAD+ (1.6 uCi...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity to PARP-1 (unknown origin) assessed as inhibition constant incubated for 1 hr by topcount microplate scintillation counter analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Inhibition of PARP1 in H202-stimulated human C41 cells incubated for 30 mins prior to H2O2-treatment measured after 10 mins by FITC-based immunostain...More data for this Ligand-Target Pair
