Found 3 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid lipoxygenase ALOX15' and Ligand = 'BDBM22302'
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
Bristol-Myers Squibb
Bristol-Myers Squibb
Affinity DataIC50: 6nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
Bristol-Myers Squibb
Bristol-Myers Squibb
Affinity DataIC50: 21nMAssay Description:Inhibition of rabbit reticulocyte 12/15-lipoxygenaseMore data for this Ligand-Target Pair