Found 5 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid lipoxygenase ALOX15' and Ligand = 'BDBM50584668' TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
Mirea Russian Technological University
Curated by ChEMBL
Mirea Russian Technological University
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Non-competitive inhibition of wild type rabbit N-terminal His-tagged ALOX15 expressed in Escherichia coli assessed as inhibition constant using linol...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mirea Russian Technological University
Curated by ChEMBL
Mirea Russian Technological University
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human N-terminal His-tagged ALOX15 expressed in Escherichia coli Rosetta2(DE3)pLysS using linoleic acid as substrate by spe...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
Mirea Russian Technological University
Curated by ChEMBL
Mirea Russian Technological University
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of wild type rabbit N-terminal His-tagged ALOX15 expressed in Escherichia coli using linoleic acid as substrate by spectrophotometric assa...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mirea Russian Technological University
Curated by ChEMBL
Mirea Russian Technological University
Curated by ChEMBL
Affinity DataIC50: 650nMAssay Description:Inhibition of recombinant human N-terminal His-tagged ALOX15 expressed in Escherichia coli Rosetta2(DE3)pLysS using arachidonic acid as substrate by ...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
Mirea Russian Technological University
Curated by ChEMBL
Mirea Russian Technological University
Curated by ChEMBL
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of wild type rabbit N-terminal His-tagged ALOX15 expressed in Escherichia coli using arachidonic acid as substrate by spectrophotometric a...More data for this Ligand-Target Pair
