Found 3 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid lipoxygenase ALOX15B' and Ligand = 'BDBM50572160' TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
University Of California Santa Cruz
Curated by ChEMBL
University Of California Santa Cruz
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:Competitive inhibition of human 15-LOX-2 assessed as equilibrium dissociation constant from catalytic site by measuring 15-HpETE by Dixon plots and D...More data for this Ligand-Target Pair
3D Structure (crystal)TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
University Of California Santa Cruz
Curated by ChEMBL
University Of California Santa Cruz
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human 15-LOX-2 assessed as enzymatic rate using arachidonic acid as substrate by UV/Vis spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
University Of California Santa Cruz
Curated by ChEMBL
University Of California Santa Cruz
Curated by ChEMBL
Affinity DataEC50: 600nMAssay Description:Inhibition of human 15-LOX-2 expressed in HEK293T cells assessed as a reduction in 15-HETE production using arachidonic acid as substrate incubated f...More data for this Ligand-Target Pair
