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Found 3 Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM209909'
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM209909(US9273014, Comparative Compound 45 | US9427442, Co...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM209909(US9273014, Comparative Compound 45 | US9427442, Co...)
Affinity DataIC50:  6.40nMAssay Description:Displacement of [3H]IN973 from gamma-secretase in human THP1 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM209909(US9273014, Comparative Compound 45 | US9427442, Co...)
Affinity DataIC50:  1.06E+3nMAssay Description:Displacement of [3H]L685458 from gamma-secretase in human THP1 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed