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Found 2 Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50498593'
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories Boston

Curated by ChEMBL
LigandPNGBDBM50498593(CHEMBL3609627)
Affinity DataIC50:  370nMAssay Description:Inhibition of gamma-secretase in human SH-SY5Y cells expressing beta-APP C-terminal fragment SPA4CT assessed as decrease of amyloid beta-42 level by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories Boston

Curated by ChEMBL
LigandPNGBDBM50498593(CHEMBL3609627)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of gamma-secretase in human SH-SY5Y cells expressing beta-APP C-terminal fragment SPA4CT assessed as decrease of amyloid beta-40 level by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed