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Found 3 Enz. Inhib. hit(s) with Target = 'Prostaglandin D2 receptor 2' and Ligand = 'BDBM50312283'
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312283((+/-)-cis-N-(1-benzoyl-2-methyl-1,2,3,4-tetrahydro...)
Affinity DataIC50:  43nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5% BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312283((+/-)-cis-N-(1-benzoyl-2-methyl-1,2,3,4-tetrahydro...)
Affinity DataIC50:  1.05E+3nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 50% human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312283((+/-)-cis-N-(1-benzoyl-2-methyl-1,2,3,4-tetrahydro...)
Affinity DataEC50:  11nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CEM cell assessed as inhibition of PGD2-induced cell migration after 3 hrs by transwell migr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed