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Found 5 Enz. Inhib. hit(s) with Target = 'Prostaglandin D2 receptor 2' and Ligand = 'BDBM50312906'
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50312906(2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl...)
Affinity DataIC50:  0.0120nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK385-7 cells assessed as inhibition of PGD2-mediated beta-arrestin translocation preincuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50312906(2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK385-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50312906(2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of mouse CRTH2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Rattus norvegicus)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50312906(2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl...)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of rat CRTH2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Cavia porcellus)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50312906(2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl...)
Affinity DataIC50:  29nMAssay Description:Inhibition of guinea pig CRTH2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed