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Found 2 Enz. Inhib. hit(s) with Target = 'Prostaglandin E synthase' and Ligand = 'BDBM50434668'
TargetProstaglandin E synthase(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50434668(CHEMBL2387503)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of mPGES1 (unknown origin)-mediated PGE2 synthesis transfected in HEK293 cells coexpressing COX1 using arachidonic acid as substrate prein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50434668(CHEMBL2387503)
Affinity DataIC50:  33nMAssay Description:Inhibition of mPGES1-mediated PGE2 release in IL1alpha-stimulated human A549 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed