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Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin E synthase' and Ligand = 'BDBM50532250'
TargetProstaglandin E synthase(Homo sapiens (Human))
University Jena

Curated by ChEMBL
LigandPNGBDBM50532250(CHEMBL4444875)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human mPGES-1 expressed in CHO-K1 cells using PGH2 as substrate assessed as PGE2 formation preincubated for 20 mins followed by additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Jena

Curated by ChEMBL
LigandPNGBDBM50532250(CHEMBL4444875)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human mPGES-1 expressed in CHO-K1 cells using PGH2 as substrate assessed as PGE2 formation preincubated for 20 mins followed by additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Jena

Curated by ChEMBL
LigandPNGBDBM50532250(CHEMBL4444875)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as PGE2-alpha formation preincubated for 60 mins prior to IL-beta stimulation measured after 24 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Jena

Curated by ChEMBL
LigandPNGBDBM50532250(CHEMBL4444875)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as PGE2-alpha formation preincubated for 60 mins prior to IL-beta stimulation measured after 24 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed