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Found 3 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM190269'
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM190269(US9180116, 6D)
Affinity DataKi:  0.890nM IC50:  2.40nMpH: 6.0Assay Description:Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM190269(US9180116, 6D)
Affinity DataEC50: <0.00100nMT: 2°CAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 ul of reduced serum medium containing 0.5% FBS. Place the p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM190269(US9180116, 6D)
Affinity DataEC50:  0.0230nMT: 2°CAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...More data for this Ligand-Target Pair
In DepthDetails US Patent