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Found 2 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50297677'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50297677(CHEMBL551829 | N-benzyl-4-(4-(methylsulfonyl)pheny...)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of human COX2 expressed in baculovirus-infected SF9 cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50297677(CHEMBL551829 | N-benzyl-4-(4-(methylsulfonyl)pheny...)
Affinity DataIC50:  8nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of lipopolysaccharide-stimulated PGE2 production after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed