Compile Data Set for Download or QSAR
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Found 1 Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM14430'
LigandPNGBDBM14430((4-chlorophenyl)[1-(3-chlorophenyl)-1H-indol-6-yl]...)
Affinity DataIC50:  36nMpH: 7.5 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase was determined by measuring the transfer of [3H]-FPP to substrate Ha-Ras-CVLS. The incorporated r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed