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Found 2 Enz. Inhib. hit(s) with Target = 'Protein kinase C theta type' and Ligand = 'BDBM50427369'
TargetProtein kinase C theta type(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50427369(CHEMBL2326012)
Affinity DataKi:  21nMAssay Description:Inhibition of full-length recombinant PKC theta (unknown origin) using ERMRPRKRQGSVRRRV as substrate after 60 mins by scintillation counting analysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50427369(CHEMBL2326012)
Affinity DataIC50:  170nMAssay Description:Inhibition of PKC-theta in human PBMC cells assessed as inhibition of IL-2 after 24 hrs by bead-based FLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed