Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Protein-S-isoprenylcysteine O-methyltransferase' and Ligand = 'BDBM50502495'
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502495(CHEMBL4445788 | US11834430, Compound 40)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50502495(CHEMBL4445788 | US11834430, Compound 40)
Affinity DataIC50:  9.5nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent