Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50107460'
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107460((S)-1-((R)-3-Phenyl-2-phenylmethanesulfonylamino-p...)
Affinity DataKi:  0.460nMAssay Description:Competitive kinetic for thrombin inhibition Ki was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107460((S)-1-((R)-3-Phenyl-2-phenylmethanesulfonylamino-p...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibitory activity against hydrolysis of thrombin was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107460((S)-1-((R)-3-Phenyl-2-phenylmethanesulfonylamino-p...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibitory activity against hydrolysis of human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed