Found 3 Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret' and Ligand = 'BDBM50563894' TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Sichuan University/Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University/Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human RET using KKKSPGEYVNIEFG as substrate incubated for 15 mins followed by Mg/ATP addition and measured after 40 mins by...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Sichuan University/Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University/Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant human RET V804M mutant using KKKVSRSGLYRSP as substrate incubated for 15 mins followed by Mg/ATP addition and measured afte...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Sichuan University/Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University/Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 163nMAssay Description:Inhibition of recombinant human RET V804L mutant using KKKVSRSGLYRSP as substrate incubated for 15 mins followed by Mg/ATP addition and measured afte...More data for this Ligand-Target Pair
